Research Article

Evaluation of Influence of Various Polymers on Dissolution and Phase Behavior of Carbamazepine-Succinic Acid Cocrystal in Matrix Tablets

Table 3

Physical evaluation of cocrystal tablets.

FormulationWeight (mg)Thickness (mm)Hardness (N)Diameter (mm)

CSH-1497.31 ± 3.504.66 ± 0.01210.34 ± 6.3010.00 ± 0.01
CSH-2372.04 ± 1.524.20 ± 0.01200.71 ± 5.1210.01 ± 0.01
CSH-3309.67 ± 243.85 ± 0.01197.56 ± 6.3510.02 ± 0.01
CSS-1495.92 ± 4.504.56 ± 0.01217.34 ± 5.1810.01 ± 0.01
CSS-2374.39 ± 2.824.13 ± 0.01205.67 ± 4.9010.01 ± 0.00
CSS-3311.71 ± 1.393.77 ± 0.01210.07 ± 7.3710.02 ± 0.00
CSK-1499.19 ± 2.174.71 ± 0.01197.01 ± 6.0510.01 ± 0.00
CSK-2308.54 ± 3.134.18 ± 0.01213.21 ± 3.5710.00 ± 0.00
CSH-3307.76 ± 4.003.86 ± 0.01208.78 ± 5.6210.02 ± 0.01