Evaluation of Influence of Various Polymers on Dissolution and Phase Behavior of Carbamazepine-Succinic Acid Cocrystal in Matrix Tablets

Table 5

Drug release kinetics from various formulations of CBZ and CBZ-SUC.

Code	Zero order ()	First order ()	Higuchi model ()	Korsmeyer-Peppas model		(h)
				()	()
CH-1	0.9673	0.9603	0.8873	0.9823	1.431	24.29
CK-1	0.9395	0.9970	0.9912	0.9998	0.625	4.84
CS-1	0.7878	0.9624	0.9252	1.0000	0.812	4.93
CH-2	0.9983	0.9960	0.9509	0.9983	1.042	15.42
CK-2	0.9893	0.9991	0.9835	0.9984	0.744	8.27
CS-2	0.8204	0.9386	0.9483	0.9856	0.322	5.68
CH-3	0.9991	0.9983	0.9632	0.9996	0.932	11.78
CK-3	0.9910	0.9949	0.9786	0.9966	0.773	12.12
CS-3	0.6579	0.8227	0.8470	1.0000	0.045	5.80
CSH-1	0.9784	0.9712	0.9079	0.9869	1.290	20.53
CSK-1	0.9926	0.9927	0.9781	0.9974	0.866	6.05
CSS-1	0.9903	0.9891	0.9728	0.9987	0.768	6.39
CSH-2	0.9987	0.9977	0.9614	0.9990	0.942	13.93
CSK-2	0.9908	0.9963	0.9765	0.9964	0.794	10.43
CSS-2	0.9101	0.9781	0.9824	0.9988	0.644	6.22
CSH-3	0.9956	0.9961	0.9712	0.9977	0.846	9.95
CSK-3	0.9861	0.9949	0.9784	0.9949	0.761	12.56
CSS-3	0.9526	0.9865	0.9818	0.9843	0.597	7.41