Research Article
Peripheral Blood Mononuclear Cell Proteome Changes in Patients with Myelodysplastic Syndrome
Table 4
Functional association of the identified protein dataset with Reactome cellular pathways.
| | Annotation (pathway/process) | XD-score | Fisher-test, value |
| | Formation of tubulin folding intermediates by CCT Tric | 3.7875 | | | Further platelet releasate | 3.1660 | | | Prefoldin mediated transfer of substrate to CCT Tric | 2.8529 | | | Activation of chaperones by IRE1 alpha | 2.4375 | | | Postchaperonin tubulin folding pathway | 2.3845 | | | Chaperonin mediated protein folding | 1.6524 | | | Formation of ATP by chemiosmotic coupling | 1.5375 | | | Smooth muscle contraction | 1.4518 | | | Cell-extracellular matrix interactions | 1.4250 | | | Glycolysis | 1.3738 | | | p53 independent DNA damage response | 1.2026 | | | Stabilization of p53 | 1.1070 | | | Regulation of ornithine decarboxylase | 1.0779 | | | VIF mediated degradation of APOBEC3G | 1.0779 | | | Platelet degranulation | 1.0545 | | | SCF beta TRCP mediated degradation of EMI1 | 1.0500 | | | Association of Tric CCT with target proteins during biosynthesis | 1.0232 | |
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