Activation of Cannabinoid Receptor 2 Enhances Osteogenic Differentiation of Bone Marrow Derived Mesenchymal Stem Cells

Figure 4

Knockdown of cannabinoid receptor 2 reduces phosphorylation of p38 MAPK. (a) Expression of phosphorylated p38 MAPK (phosphor-p38 MAPK) in BMSCs infected with virus containing mock sequence or siRNA sequence against cannabinoid receptor 2 (CNR2). Bar = 100 μm. (b) Quantification of immunofluorescent (IF) images shows that less siRNA infected BM-MSCs are positive for phosphor-p38 MAPK than mock infected BM-MSCs ().

(a)

(b)