Dissecting the Role of Curcumin in Tumour Growth and Angiogenesis in Mouse Model of Human Breast Cancer

Figure 2

Curcumin inhibits the tumor growth in xenograft mouse model of breast cancer. (a) Curcumin inhibits tumor growth in breast tumor xenograft model. Breast tumor growth in 8 mice treated with vehicle (•) and 8 mice treated with curcumin (■). Tumor volumes decreased significantly after 3 weeks of curcumin treatment until 6 weeks () as compared with control (vehicle-treated). (b) Ex vivo tumour from control (left) and treated mice (right). (c) Measurements of fluorescence per second depicting microvessel tumor (FITC-DEXTRANE) using MacroFluo images showed that curcumin inhibits the angiogenesis in tumour of mice treated with curcumin (right) with respect to controls (left).

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