Formulation of Novel Layered Sodium Carboxymethylcellulose Film Wound Dressings with Ibuprofen for Alleviating Wound Pain

Table 1

Preparation of layered films.

Film	1st step	2nd step	3rd step	4th step
0.5-Ibu-1	NaCMC → Sanatyl → pre-drying	1% Ibu sol. → evaporation	NaCMC	pre-drying and drying
0.5-Ibu-2	NaCMC → Sanatyl → pre-drying	NaCMC with Ibu	—	pre-drying and drying
1.0-Ibu-1	NaCMC → Sanatyl → pre-drying	2% Ibu sol. → evaporation	NaCMC	pre-drying and drying
1.0-Ibu-2	NaCMC → Sanatyl → pre-drying	NaCMC with Ibu	—	pre-drying and drying
1-blank	NaCMC → Sanatyl → pre-drying	acetone → evaporation	NaCMC	pre-drying and drying
2-blank	NaCMC → Sanatyl → pre-drying	NaCMC	—	pre-drying and drying
3-blank	NaCMC → pre-drying	acetone → evaporation	NaCMC	pre-drying and drying
4-blank	NaCMC → pre-drying	NaCMC	—	pre-drying and drying
0.5-Ibu-1 without Sanatyl	NaCMC → pre-drying	1% Ibu sol. → evaporation	NaCMC	pre-drying and drying
0.5-Ibu-2 without Sanatyl	NaCMC → pre-drying	NaCMC with Ibu	—	pre-drying and drying