Research Article

Comparative Analysis of Methods to Induce Myocardial Infarction in a Closed-Chest Rabbit Model

Table 1

Distribution and follow-up depending on embolization site.

Embolization site
()
Intraoperative events3-week survival
()
Echographic assessmentHistologic assessment

LAD
 Proximal segment ()VF0Transmural infarct
 Mid segment ()VF0Transmural infarct
 Distal segment ()ACD0Transmural infarct
 S. branch vessel ()1No LV dysfunctionNontransmural infarct
CA
 Proximal segment ()NSVT, CHF0Transmural infarct
 Mid segment ()NSVT2LV dysfunctionTransmural infarct
 Distal segment ()
 S. branch vessel ()2No LV dysfunctionNontransmural infarct
RCA
 Proximal segment ()CHF0Transmural infarct
 Mid segment ()NSVT2LV and RV dysfunctionTransmural infarct
 Distal segment ()

LAD: left anterior descending; CA: circumflex artery; RCA: right coronary artery; LV: left ventricle; RV: right ventricle; VF: ventricular fibrillation; ACD: atrioventricular conduction disorder; NSVT: nonsustained ventricular tachycardia; CHF: congestive heart failure; S. branch vessel: secondary branch vessel.