MUTYH Gene Polymorphisms as Risk Factors for Rheumatoid Arthritis

Table 3

Odds ratios and 95% confidence intervals for the association between MUTYH gene haplotypes and RA.

Haplotype	rs3219463	rs3219476	rs3219489	rs3219493	RA, %	Control, %	value/ value	Odds ratio (95% CI)
Ht1	G	G	G	G	150 (39.1)	173 (45.1)	0.0927/0.7416	0.78 (0.59–1.04)
Ht2	A	T	C	G	124 (32.3)	102 (26.6)	0.0815/0.652	1.32 (0.97–1.80)
Ht3	G	T	C	G	19 (4.9)	11 (2.9)	0.1362/1.0896	1.77 (0.83–3.76)
Ht4	A	G	C	G	17 (4.4)	15 (3.9)	0.718/5.744	1.14 (0.56–2.32)
Ht5	G	T	G	G	13 (3.4)	12 (3.1)	0.8389/6.7112	1.09 (0.49–2.41)
Ht6	G	T	G	C	13 (3.4)	30 (7.8)	0.0076^*/0.0608	0.41 (0.21–0.81)
Ht7	A	G	G	G	11 (2.9)	19 (4.9)	0.1362/1.0896	0.57 (0.27–1.21)
Ht8	G	G	C	G	7 (1.8)	21 (5.5)	0.007^*/0.056	0.32 (0.13–0.76)

95% CI: 95% confidence intervals.
value of <0.05 was determined as statistically significant.
The chi-square test was performed to obtain the value.
value: value corrected by Bonferroni correction.