The structure of Mycobacterium tuberculosis
isocitrate lyase in ribbon representation. (a) ICL tetramer with each subunit is represented by different colors [5
]. (b) ICL monomer with active site (in cyan color) in “open conformation” and (c) ICL monomer with active site (in cyan color) in “close conformation” substrates (succinate and glyoxylate) are bound in the active site with red CPK representation.