Fructose-Drinking Water Induced Nonalcoholic Fatty Liver Disease and Ultrastructural Alteration of Hepatocyte Mitochondria in Male Wistar Rat

Table 1

Effects of fructose-drinking water on metabolic variables in C and F20 groups for 8 weeks.

Variables	C		F20
	Baseline	8 weeks	Baseline	8 weeks
Body weight gain (%)	—	36.12 ± 0.81	—	43.03 ± 0.76^a
Body mass index (g/cm^2)	0.64 ± 0.01	0.66 ± 0.02	0.64 ± 0.02	0.91 ± 0.02^ab
Abdominal circumference (cm)	16.5 ± 0.26	18.3 ± 0.1	16.1 ± 0.40	22.9 ± 0.3^ab
Total abdominal fat (mg/mm tibial length)	—	196.72 ± 23.13	—	437.97 ± 27.08^a
Plasma triglyceride (mmol/L)	0.70 ± 0.09	0.65 ± 0.08	0.78 ± 0.07	1.22 ± 0.14^ab
Plasma total cholesterol (mmol/L)	1.5 ± 0.01	1.6 ± 0.1	1.5 ± 0.04	1.5 ± 0.1
Systolic blood pressure (mmHg)	103.3 ± 1.1	105.0 ± 1.8	101.3 ± 2.1	145.8 ± 1.5^ab
Plasma glucose (mmol/L)	5.1 ± 0.4	6.4 ± 0.2	4.7 ± 0.4	8.1 ± 0.6^ab

Values are mean ± SEM and = 6 for each group. Superscripts letters are significantly different. ^aA significant difference as compared to C group at 8 weeks. ^bA significant difference within groups as compared to baseline.