Icariin Intervenes in Cardiac Inflammaging through Upregulation of SIRT6 Enzyme Activity and Inhibition of the NF-Kappa B Pathway

Figure 3

(a) shows a western analysis with a band of the expected size corresponding to NF-κB (p65) protein in mouse heart tissue extract prepared from 3-month old mice (young), 24-month old mice (aged), and 24-month old mice treated with ICA (aged + ICA) (a). Numbers in brackets are the normalized OD (optical density) values. (b) shows the normalized OD value comparison of NF-κB (p65) protein expression in heart tissue (fold increase compared with the control young group set at 1.0). Note: aged group compared with the young group, ; aged group compared with the aged group + ICA intervention group, .

(a)

(b)