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BioMed Research International
Volume 2015, Article ID 897971, 9 pages
http://dx.doi.org/10.1155/2015/897971
Research Article

Gender-Specific Associations of Serum Antibody to Porphyromonas gingivalis and Inflammatory Markers

1Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka 812-8582, Japan
2Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, Nagoya 464-8650, Japan
3Japanese Red Cross Kumamoto Healthcare Center, Kumamoto 861-8528, Japan
4Section of Periodontology, Division of Oral Rehabilitation, Kyushu University Faculty of Dental Science, Fukuoka 812-8582, Japan

Received 28 October 2014; Revised 24 December 2014; Accepted 24 December 2014

Academic Editor: Kazuhiko Nakano

Copyright © 2015 Michiko Furuta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. World Health Organization, Oral Health, 2012, http://www.who.int/mediacentre/factsheets/fs318/en/.
  2. B. L. Pihlstrom, B. S. Michalowicz, and N. W. Johnson, “Periodontal diseases,” The Lancet, vol. 366, no. 9499, pp. 1809–1820, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. R. J. Genco, “Current view of risk factors for periodontal diseases,” Journal of Periodontology, vol. 67, no. 10, supplement, pp. 1041–1049, 1996. View at Publisher · View at Google Scholar · View at Scopus
  4. J. J. Zambon, “Periodontal diseases: microbial factors,” Annals of Periodontology, vol. 1, no. 1, pp. 879–925, 1996. View at Publisher · View at Google Scholar · View at Scopus
  5. A. D. Haffajee and S. S. Socransky, “Microbial etiological agents of destructive periodontal diseases,” Periodontology 2000, vol. 5, pp. 78–111, 1994. View at Publisher · View at Google Scholar · View at Scopus
  6. J. L. Ebersole and M. A. Taubman, “The protective nature of host responses in periodontal diseases.,” Periodontology 2000, vol. 5, pp. 112–141, 1994. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Kojima, K. Yano, and I. Ishikawa, “Relationship between serum antibody levels and subgingival colonization of Porphyromonas gingivalis in patients with various types of periodontitis,” Journal of Periodontology, vol. 68, no. 7, pp. 618–625, 1997. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Nakagawa, S. Yamada, M. Tsunoda et al., “Clinical, microbiological, and immunological studies following initial preparation in adult periodontitis,” The Bulletin of Tokyo Dental College, vol. 31, no. 4, pp. 321–331, 1990. View at Google Scholar · View at Scopus
  9. Y. Furuichi, H.-O. Ito, Y. Izumi et al., “Periodontal status and serum antibody titers for Porphyromonas gingivalis fimbriae in a rural population in Japan,” Journal of Clinical Periodontology, vol. 28, no. 3, pp. 264–269, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. R. G. Craig, R. Boylan, J. Yip et al., “Serum IgG antibody response to periodontal pathogens in minority populations: relationship to periodontal disease status and progression,” Journal of Periodontal Research, vol. 37, no. 2, pp. 132–146, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Kudo, K. Naruishi, H. Maeda et al., “Assessment of the plasma/serum IgG test to screen for periodontitis,” Journal of Dental Research, vol. 91, no. 12, pp. 1190–1195, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. M. I. Fredriksson, C. M. S. Figueredo, A. Gustafsson, K. G. Bergström, and B. E. Åsman, “Effect of periodontitis and smoking on blood leukocytes and acute-phase proteins,” Journal of Periodontology, vol. 70, no. 11, pp. 1355–1360, 1999. View at Publisher · View at Google Scholar · View at Scopus
  13. B. Noack, R. J. Genco, M. Trevisan, S. Grossi, J. J. Zambon, and E. de Nardin, “Periodontal infections contribute to elevated systemic C-reactive protien level,” Journal of Periodontology, vol. 72, no. 9, pp. 1221–1227, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. N. Esser, S. Legrand-Poels, J. Piette, A. J. Scheen, and N. Paquot, “Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes,” Diabetes Research and Clinical Practice, vol. 105, no. 2, pp. 141–150, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. J. M. Albandar, “Global risk factors and risk indicators for periodontal diseases,” Periodontology 2000, vol. 29, no. 1, pp. 177–206, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Furuta, Y. Shimazaki, T. Takeshita et al., “Gender differences in the association between metabolic syndrome and periodontal disease: the Hisayama Study,” Journal of Clinical Periodontology, vol. 40, no. 8, pp. 743–752, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Ainamo, D. Barmes, G. Beagrie, T. Cutress, J. Martin, and J. Sardo-Infirri, “Development of the World Health Organization (WHO) community periodontal index of treatment needs (CPITN),” International Dental Journal, vol. 32, no. 3, pp. 281–291, 1982. View at Google Scholar · View at Scopus
  18. I. Morita, H. Nakagaki, S. Yoshii et al., “Gradients in periodontal status in Japanese employed males,” Journal of Clinical Periodontology, vol. 34, no. 11, pp. 952–956, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. K. G. M. M. Alberti, R. H. Eckel, S. M. Grundy et al., “Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity,” Circulation, vol. 120, no. 16, pp. 1640–1645, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. T. Kawada, “Smoking-induced leukocytosis can persist after cessation of smoking,” Archives of Medical Research, vol. 35, no. 3, pp. 246–250, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. Momiyama, A. Kawaguchi, I. Kajiwara et al., “Prognostic value of plasma high-sensitivity C-reactive protein levels in Japanese patients with stable coronary artery disease: the Japan NCVC-Collaborative Inflammation Cohort (JNIC) study,” Atherosclerosis, vol. 207, no. 1, pp. 272–276, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. K. H. Allin and B. G. Nordestgaard, “Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer,” Critical Reviews in Clinical Laboratory Sciences, vol. 48, no. 4, pp. 155–170, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Murayama, A. Nagai, K. Okamura et al., “Serum immunoglobulin G antibody to periodontal bacteria,” Advances in dental research, vol. 2, no. 2, pp. 339–345, 1988. View at Google Scholar · View at Scopus
  24. J. D. Beck, P. Eke, G. Heiss et al., “Periodontal disease and coronary heart disease: a reappraisal of the exposure,” Circulation, vol. 112, no. 1, pp. 19–24, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. J. L. Ebersole, M. A. Taubman, D. J. Smith, D. E. Frey, A. D. Haffajee, and S. S. Socransky, “Human serum antibody responses to oral microorganisms. IV. Correlation with homologous infection,” Oral Microbiology and Immunology, vol. 2, no. 2, pp. 53–59, 1987. View at Publisher · View at Google Scholar · View at Scopus
  26. D. M. Anderson, J. L. Ebersole, and M. J. Novak, “Functional properties of nonhuman primate antibody to Porphyromonas gingivalis,” Infection and Immunity, vol. 63, no. 9, pp. 3245–3252, 1995. View at Google Scholar · View at Scopus
  27. P. N. Papapanou, A. M. Neiderud, E. Disick, E. Lalla, G. C. Miller, and G. Dahlén, “Longitudinal stability of serum immunoglobulin G responses to periodontal bacteria,” Journal of Clinical Periodontology, vol. 31, no. 11, pp. 985–990, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. H. J. Shiau and M. A. Reynolds, “Sex differences in destructive periodontal disease: exploring the biologic basis,” Journal of Periodontology, vol. 81, no. 11, pp. 1505–1517, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. E. N. Fish, “The X-files in immunity: sex-based differences predispose immune responses,” Nature Reviews Immunology, vol. 8, no. 9, pp. 737–744, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. J. L. Rinn and M. Snyder, “Sexual dimorphism in mammalian gene expression,” Trends in Genetics, vol. 21, no. 5, pp. 298–305, 2005. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Paraskevas, J. D. Huizinga, and B. G. Loos, “A systematic review and meta-analyses on C-reactive protein in relation to periodontitis,” Journal of Clinical Periodontology, vol. 35, no. 4, pp. 277–290, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. R. H. Straub, “The complex role of estrogens in inflammation,” Endocrine Reviews, vol. 28, no. 5, pp. 521–574, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. J. Pfeilschifter, R. Köditz, M. Pfohl, and H. Schatz, “Changes in proinflammatory cytokine activity after menopause,” Endocrine Reviews, vol. 23, no. 1, pp. 90–119, 2002. View at Publisher · View at Google Scholar · View at Scopus
  34. C. M. Gameiro, F. Romão, and C. Castelo-Branco, “Menopause and aging: changes in the immune system—a review,” Maturitas, vol. 67, no. 4, pp. 316–320, 2010. View at Publisher · View at Google Scholar · View at Scopus
  35. D. L. Cochran, “Inflammation and bone loss in periodontal disease,” Journal of Periodontology, vol. 79, no. 8, supplement, pp. 1569–1576, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. N. Pischon, N. Heng, J.-P. Bernimoulin, B.-M. Kleber, S. N. Willich, and T. Pischon, “Obesity, inflammation, and periodontal disease,” Journal of Dental Research, vol. 86, no. 5, pp. 400–409, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Novella, M. Heras, C. Hermenegildo, and A. P. Dantas, “Effects of estrogen on vascular inflammation: a matter of timing,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 32, no. 8, pp. 2035–2042, 2012. View at Publisher · View at Google Scholar · View at Scopus