Gender-Specific Associations of Serum Antibody to Porphyromonas gingivalis and Inflammatory Markers
Table 4
Prevalence ratios for periodontal disease in 2011.
Periodontally healthy in 2003
Periodontal disease in 2003
Males
Females
Males
Females
PR (95% CI)†
PR (95% CI)†
PR (95% CI)†
PR (95% CI)†
Model 1
Serum antibody titer against Pg
1.04 (0.94–1.14)
1.11 (0.93–1.32)
1.00 (0.97–1.03)
1.16 (1.04–1.30
Overweight
No
1
1
1
1
Yes
1.01 (0.58–1.75)
0.93 (0.39–2.24)
0.82 (0.66–1.01)
0.72 (0.28–1.87)
hsCRP
Normal
1
1
1
1
Elevated hsCRP
1.27 (0.70–2.29)
6.10 (1.22–30.31
0.99 (0.82–1.19)
3.00 (1.08–8.31
Leukocytes‡
0.96 (0.86–1.05)
0.90 (0.67–1.20)
1.01 (0.98–1.04)
0.97 (0.87–1.10)
Model 2
Serum antibody titer against Pg
Low
1
1
1
1
High
1.05 (0.61–1.82)
0.85 (0.25–2.94)
0.96 (0.81–1.13)
2.21 (1.04–4.73
Overweight
No
1
1
1
1
Yes
1.03 (0.59–1.80)
1.04 (0.31–3.45)
0.81 (0.65–1.00)
0.80 (0.23–2.74)
hsCRP
Normal
1
1
1
1
Elevated hsCRP
1.25 (0.70–2.26)
5.96 (1.31–27.13
1.00 (0.83–1.20)
3.70 (1.07–12.80
Leukocytes‡
0.96 (0.86–1.05)
0.90 (0.66–1.22)
1.01 (0.98–1.04)
0.99 (0.88–1.12)
Dependent variable, 1: periodontal disease in 2011, 0: periodontally healthy in 2011. Model 1: continuous variable of serum antibody titer against Pg was included. Model 2: categorical variable of serum antibody titer against Pg was included. < 0.05, < 0.01. Adjusted by age, smoking, toothbrushing frequency, triglycerides, HDL, fasting glucose, and systolic blood pressure in 2003. Continuous variable of leukocytes was used, because of small number of elevated leukocytes. HsCRP, high-sensitive C-reactive protein; PR, prevalence ratio; CI, confidence interval.
