Research Article
Morphological Findings in Trophozoites during Amoebic Abscess Development in Misoprostol-Treated BALB/c Mice
Table 1
Percentage of damage obtained in E. histolytica infected animals treated or not with MPL.
| Specie | Treatment | Days p.i. | Weight (g) | Damage (%) | Liver | Abscess |
| Hamster | — | 2 | 5.8 ± 1.3 | 0.6 ± 0.1 | 10 ± 2 | — | 4 | 6.5 ± 1.5 | 1.3 ± 0.8 | 18 ± 7 | — | 7 | 11.5 ± 4 | 4.1 ± 0.4 | 35 ± 2 |
| Mice | — | 2 | 1.9 ± 0.4 | 0.227 ± 0.09 | 11 ± 5 | MPL | 2 | 2.4 ± 0.4 | 0.215 ± 0.01 | 12 ± 3 | — | 4 | 2.38 ± 0.9 | 0.236 ± 0.09 | 10 ± 2 | MPL | 4 | 2.3 ± 0.4 | 0.273 ± 0.10 | 12 ± 2 | — | 7 | 2.3 ± 0.4 | 0.191 ± 0.10 | 8 ± 0.1 | MPL | 7 | 2.3 ± 0.2 | 0.192 ± 0.04 | 8 ± 0.1 |
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versus liver weight from noninfected hamsters.
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