BioMed Research International / 2015 / Article / Tab 2

Research Article

The Effect of Bicarbonate Administration via Continuous Venovenous Hemofiltration on Acid-Base Parameters in Ventilated Patients

Table 2

Baseline patient characteristics by partial arterial pressure of carbon dioxide at time of continuous venovenous hemofiltration initiationa.

PatientsCO2 ≤ 40 mmHgCO2 > 40 mmHg
()b()()

Age57.5 ± 15.461.8 ± 17.355.2 ± 13.0
Male13 (68.4)6 (66.7)7 (77.8)
ICU type
 Medical7 (36.8)3 (33.3)3 (33.3)
 Surgicalc7 (36.8)4 (44.5)3 (33.3)
 Cardiac5 (26.2)2 (22.2)3 (33.3)
ICU admission diagnosis
 Sepsis5 (26.3)2 (22.2)2 (22.2)
 Heart failure/cardiogenic shock6 (31.6)1 (11.1)5 (55.6)
 Respiratory failure/pneumonia7 (36.8)5 (55.6)2 (22.2)
 Other causesd1 (5.3)1 (11.1)0
Preexisting comorbid condition
 Hypertension10 (52.6)5 (55.6)5 (55.6)
 Coronary artery disease5 (26.3)1 (11.1)4 (44.4)
 Chronic kidney diseasee7 (36.8)2 (22.2)5 (55.6)
 Diabetes mellitus10 (52.6)2 (22.2)7 (77.8)
 Liver disease1 (5.3)00
 COPD6 (31.5)3 (33.3)2 (22.2)
 Cancer7 (36.8)3 (33.3)4 (44.4)
Systolic blood pressure (mmHg)95.6 ± 16.2100.8 ± 14.489.3 ± 17.3
Vasopressor dependency14 (73.7)6 (66.7)8 (88.9)
Urine output (mL)f14.6 (17.1)12.6 ± 17.417.2 ± 18.4
SOFA scoreg13.4 ± 3.512.8 ± 4.114.0 ± 2.7
pHg7.32 ± 0.127.40 ± 0.067.24 ± 0.12
Creatinine (mg/dL)3.9 ± 1.23.8 ± 1.03.8 ± 1.3
Blood urea nitrogen (mg/dL)68.4 ± 35.857.2 ± 29.472.1 ± 36.3
Potassium (mmol/L)4.9 ± 1.04.5 ± 1.25.2 ± 0.8
Lactate (mmol/L)h4.1 ± 4.94.7 ± 5.63.4 ± 4.2
White blood cell count (K/L)15.7 ± 6.615.6 ± 5.517.1 ± 7.1
Platelets (K/L)135 ± 111120 ± 90163 ± 130
Mortality within 7 days of CVVH initiation2 (10.5)02 (22.2)

Values presented as mean ± standard deviation or (%).
b1 of 19 patients did not have a starting arterial blood gas.
cIncluding surgical, cardiothoracic, and cardiac surgery ICUs.
dRetroperitoneal bleed.
eIncluding 1 end stage renal disease patient on dialysis.
fUrine output in 1-hour period prior to starting CVVH.
.
for all patients, for CO2 ≤ 40 mmHg, and for CO2 > 40 mmHg.
ICU: intensive care unit; CVVH: continuous venovenous hemofiltration; COPD: chronic obstructive pulmonary disease, K: 1000, and CO2: partial arterial pressure of carbon dioxide.

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