BioMed Research International / 2015 / Article / Tab 3

Research Article

The Effect of Bicarbonate Administration via Continuous Venovenous Hemofiltration on Acid-Base Parameters in Ventilated Patients

Table 3

Acid-base parameters and electrolytesa.

Hour 0Hour 8Hour 16Hour 24Hour 36Hour 48Hour 60Hour 72Hour 96

pH7.32 ± 0.127.37 ± 0.087.37 ± 0.107.37 ± 0.087.39 ± 0.097.37 ± 0.087.38 ± 0.077.38 ± 0.077.37 ± 0.11
(n = 18)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 18)(n = 17)

CO2 (mmHg)42.0 ± 14.637.3 ± 12.638.1 ± 9.739.9 ± 10.340.1 ± 11.639.4 ± 11.640.6 ± 10.342.2 ± 10.243.8 ± 16.1
(n = 18)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 18)(n = 17)

HCO3 (mmol/L)b19.8 ± 5.120.1 ± 5.119.7 ± 4.222.3 ± 3.922.8 ± 3.723.1 ± 3.222.8 ± 3.523.3 ± 2.423.2 ± 3.8
(n = 19)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 16)(n = 16)

Base excess (mmol/L)−5.2 ± 6.5−4.2 ± 5.4−3.9 ± 5.4−3.3 ± 3.6−2.2 ± 3.0−2.3 ± 2.7−1.8 ± 3.3−1.2 ± 2.6−1.4 ± 3.3
(n = 18)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 18)(n = 17)

Sodium (mmol/L)132.7 ± 6.5132.8 ± 5.1132.5 ± 5.6132.5 ± 5.9132.1 ± 3.9132.1 ± 3.9132.1 ± 4.2132.4 ± 4.1131.1 ± 3.8
(n = 19)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 16)(n = 16)

Potassium (mmol/L)4.9 ± 1.04.6 ± 0.84.6 ± 0.74.6 ± 0.74.5 ± 0.64.5 ± 0.84.4 ± 0.44.3 ± 0.54.5 ± 0.5
(n = 19)(n = 19)(n = 18)(n = 19)(n = 19)(n = 19)(n = 18)(n = 17)(n = 16)

Chloride (mmol/L)96.4 ± 6.297.2 ± 5.797.4 ± 4.597.3 ± 5.498.5 ± 4.699.2 ± 3.598.2 ± 4.199.3 ± 3.798.8 ± 4.0
(n = 19)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 16)(n = 16)

Ionized calcium (mg/dL)1.03 ± 0.11.08 ± 0.31.05 ± 0.11.04 ± 0.11.03 ± 0.11.08 ± 0.11.09 ± 0.11.11 ± 0.11.11 ± 0.1
(n = 19)(n = 16)(n = 17)(n = 19)(n = 18)(n = 16)(n = 18)(n = 16)(n = 15)

BUN (mg/dL)68.4 ± 35.860.2 ± 33.251.8 ± 27.145.4 ± 22.540.1 ± 20.237.5 ± 18.934.1 ± 16.430.5 ± 15.229.4 ± 14.6
(n = 19)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 16)(n = 16)

Creatinine (mg/dL)3.9 ± 1.23.5 ± 1.23.1 ± 1.12.8 ± 1.02.4 ± 1.02.3 ± 0.82.0 ± 0.72.0 ± 0.71.7 ± 0.7
(n = 19)(n = 18)(n = 18)(n = 18)(n = 19)(n = 17)(n = 18)(n = 16)(n = 16)

Values presented as mean ± standard deviation.
bDrawn from venous chemistry panel.
CO2: partial arterial pressure of carbon dioxide, HCO3: bicarbonate, and BUN: blood urea nitrogen.

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