Assessment of Functional Characteristics of Amnestic Mild Cognitive Impairment and Alzheimer’s Disease Using Various Methods of Resting-State FMRI Analysis

Table 1

Demographic and clinical findings of healthy subjects and patients with amnestic mild cognitive impairment (aMCI) or Alzheimer’s disease (AD).

	Healthy subjects	aMCI	AD	value
Number of subjects	62	34	37
MMSE score	28.6 ± 1.9	27.1 ± 2.1	16.8 ± 6.9	< 0.0001
Age	68.5 ± 8.0	68.4 ± 7.9	72.8 ± 8.2	< 0.03
Sex (M/F)	17/45	18/16	10/27	< 0.03
Education	10.9 ± 5.2	11.5 ± 5.2	10.9 ± 5.3	> 0.25

Data for age, education, and MMSE (mini-mental state examination) score: mean ± SD; M, male; F, female. The value was obtained by one-way ANOVA and chi-square test.