Activation of Apoptotic Signal in Endothelial Cells through Intracellular Signaling Molecules Blockade in Tumor-Induced Angiogenesis
Table 2
EC phenotype classification and fate for inhibition of each intracellular signaling molecule before blood flow. The four combinations of Cadherin and Rac are shown in the top row. The row corresponding to “None” shows the cell phenotype when no molecule is blocked and EC fate is considered as wild type. The third row shows abbreviation of each phenotype. P stands for proliferation, A stands for apoptosis, M stands for motility, and L stands for lumen formation. One and 0 in each row determine activation and deactivation of each cell phenotype. The last column is EC fate.
