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BioMed Research International
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2015
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Article
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Tab 2
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Research Article
Screening Active Compounds from
Garcinia
Species Native to China Reveals Novel Compounds Targeting the STAT/JAK Signaling Pathway
Table 2
The IC50s for GB32, GB39, and GB40 against the JAK1, JAK2, JAK3, and Tyk2 enzymes.
IC50 [
M]
GB32
GB39
GB40
JAK1
>40
12.2 ± 0.3
14.2 ± 0.4
JAK2
37.3 ± 6.9
1.7 ± 0.1
1.4 ± 0.1
JAK3
17.5 ± 1.5
3.8 ± 0.3
3.2 ± 0.2
Tyk2
>40
13 ± 1.6
12.9 ± 0.9