BioMed Research International / 2015 / Article / Fig 2

Research Article

Trigonella foenum (Fenugreek) Induced Apoptosis in Hepatocellular Carcinoma Cell Line, HepG2, Mediated by Upregulation of p53 and Proliferating Cell Nuclear Antigen

Figure 2

Fenugreek seed crude extract (FCE) induced changes in HepG-2 cell line morphology. The results revealed that the control cells showed a typical polygonal and intact appearance, whereas the 100~500 μg/mL range of FCE-treated cells displayed morphological changes with preapoptotic characteristics. Representative data from three independent experiments are shown, using inverted phase contrast microscope at 200x magnification.