Trigonella foenum (Fenugreek) Induced Apoptosis in Hepatocellular Carcinoma Cell Line, HepG2, Mediated by Upregulation of p53 and Proliferating Cell Nuclear Antigen

Figure 4

Effect of Fenugreek seed crude extract (FCE) on caspase-3 activity (as indicated by (DEVD-pNA) cleavage) of HepG2 cells. Cells were treated with or without 100~500 μg/mL range of FCE for 48 h. Cells without drug treatment were used as controls. as compared to the untreated controls, using the unpaired Student -test. Each data point is an average of three independent experiments and is expressed as M ± SD. More details are under Section 2.