Research Article

Influence of Genetic Variants in EGF and Other Genes on Hematological Traits in Korean Populations by a Genome-Wide Approach

Figure 2

A regional association plot of the novel genetic locus associated with PLT. Round shaped dots represent −log10 values of SNPs from combined meta-analyses (discovery and replication stages). Diamond shaped purple dot that is located in the center of 0.8 Mb of 4q25 genomic region indicates the strongest signal associated with PLT. The color of each dot indicates the level of linkage disequilibrium (LD), , relative to the SNP rs2282786. At the bottom, the locations of RefSeq genes are represented. Plot was generated from JPT + CHB panel based on hg18 HapMap phase 2 using LocusZoom.