Garcinia dulcis Fruit Extract Induced Cytotoxicity and Apoptosis in HepG2 Liver Cancer Cell Line

Figure 2

Apoptosis study upon treatment of the methanolic flesh extract of G. dulcis at IC₅₀ value. The distribution of cells undergoing early and late apoptosis together with viable cells was determined at 24 hours (a), 48 hours (b), and 72 hours (c) in comparison to respective control, using Annexin V-FITC and propidium iodide flow cytometric analysis. The values are presented as mean ± standard deviation, where indicated significant difference relative to control (). The representative flow cytometric scans of untreated HepG2 cells and those treated with methanolic flesh extract of G. dulcis for 24, 48, and 72 hours are presented in Figures (d) to (g), respectively.

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