The Gastrointestinal Irritation of Polygala Saponins and Its Potential Mechanism In Vitro and In Vivo

Figure 3

Effects of Onjisaponin B (OJB), tenuifolin (TEN), and senegenin (SNG) on isolated gut motility in rabbit. Mark: the solution was prepared and diluted to different concentrations (8, 4, and 2 mg/mL) for isolated gut motility experiment, 200 uL were added into per 20 mL Tyrode’s solution, measuring the average tension 3 min before and after the administration by the method of interval measurement.