Research Article
Resveratrol Prevents Cardiovascular Complications in the SHR/STZ Rat by Reductions in Oxidative Stress and Inflammation
Table 1
Physiological and biochemical parameters following resveratrol administration to control (WKY + THC) and diabetic rats (STZ + THC).
| | Parameter | WKY | WKY + Res | SHR/STZ | SHR/STZ + Res |
| | Systolic blood pressure (mmHg) | 149 ± 11 | 157 ± 6 | 223 ± 9 | 215 ± 9 | | Heart rate (BMP) | 439 ± 4 | 413 ± 12 | 409 ± 9 | 389 ± 11 | | Left ventricular mass (mg/g body mass) | 2.3 ± 0.03 | 2.3 ± 0.04 | 2.8 ± 0.07 | 2.7 ± 0.07 | | Right ventricular mass (mg/g body mass) | 0.5 ± 0.02 | 0.5 ± 0.04 | 0.5 ± 0.02 | 0.5 ± 0.02 | | Kidney mass (mg/g body mass) | 6.1 ± 0.1 | 5.8 ± 0.1 | | | | Blood glucose (mmol/L) | 10.4 ± 0.7 | 9.8 ± 0.7 | 32.8 ± 1.5 | 29.9 ± 1.1 | | Serum nitric oxide (mol) | 6.1 ± 0.5 | 7.1 ± 0.8 | 4.2 ± 0.3 | 5.7 ± 0.3 | | Serum malondialdehyde (μmol) | 62.2 ± 2.7 | 60.2 ± 2.5 | 127.8 ± 5.7 | 108.7 ± 4.7 | | Serum interleukin-1 (ng/mL) | 4.8 ± 0.1 | 4.8 ± 0.1 | 6.1 ± 0.3 | 5.2 ± 0.2 | | Serum interleukin-6 (ng/mL) | 3.1 ± 0.1 | 3.4 ± 0.1 | 3.4 ± 0.1 | 3.5 ± 0.1 |
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Values are presented as mean ± SEM. versus WKY.
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