Gray and White Matter Volumes and Cognitive Dysfunction in Drug-Naïve Newly Diagnosed Pediatric Epilepsy

Figure 2

Correlations between VBM results and cognitive functions in patients with newly diagnosed pediatric epilepsy and control subjects. Association patterns between structural findings and cognitive functions showed some differences between the groups. Lower scores in freedom from distractibility were correlated with decreased WM volumes in the right parahippocampal and the middle temporal gyri and the left frontal subgyral, precuneus, and the superior parietal lobule areas in the control group (corrected ) (a). However, lower scores in freedom from distractibility were correlated with decreased GM volumes in the left postcentral gyrus in the epilepsy group (corrected ) ((b) and (c)). Please also note Table 5 for coordinates and more detailed information. L, left; R, right.

(a)

(b)

(c)