Gray and White Matter Volumes and Cognitive Dysfunction in Drug-Naïve Newly Diagnosed Pediatric Epilepsy

Figure 3

Correlations between VBM results and cognitive functions in patients with newly diagnosed pediatric epilepsy and control subjects. Association patterns between structural findings and cognitive functions showed clear differences between the groups. In the control group, poor performance in the Stroop-color test (longer response time) was correlated with decreased GM volume in the right posterior lobe and decreased WM volumes of the right frontal subgyral and insular areas and the left sublobar region (a). In contrast, in the epilepsy group, a longer response time in the Stroop-color test was correlated with decreased GM volume only of the right superior temporal gyrus in the epilepsy group ((b) and (c)). Please also note Table 5 for coordinates and more detailed information. L, left; R, right.

(a)

(b)

(c)