Research Article

Gray and White Matter Volumes and Cognitive Dysfunction in Drug-Naïve Newly Diagnosed Pediatric Epilepsy

Table 5

Brain regions correlated with intelligence scores in the control and epilepsy groups for Figures 1(c), 2, and 3.

GroupCognitive subdomainAnatomical regionsCoordinateCluster sizeCluster-level corrected value
()

ControlVerbal IQLeft superior temporal gyrus, Gray Matter14
1983
<0.001
Left anterior cingulate gyrus, Gray Matter15721<0.001
Left superior temporal gyrus, White Matter 26
934
<0.001
Right parahippocampal gyrus, White Matter3213973<0.001

Control Freedom from distractibilityLeft frontal lobe, Subgyral, White Matter851
<0.001
Left parietal lobe, precuneus, White Matter174249520.016
Left superior parietal lobule, White Matter45
2208
<0.001
Right parahippocampal gyrus, White Matter3236365<0.001
Right middle temporal gyrus, White Matter38192015<0.001

ControlStroop-colorRight posterior lobe, Gray Matter334779 <0.001
Right frontal lobe, Subgyral, White Matter23
30
0
1034
0.005
Right insular, White Matter40813600.001
Left cerebrum, Sublobar, White Matter152472<0.001

EpilepsyFreedom from distractibilityLeft postcentral gyrus, Gray Matter607660.033

EpilepsyStroop-colorRight superior temporal gyrus, Gray Matter19124750.033

IQ: intelligence quotient.