Patient Acceptable Symptom State in Self-Report Questionnaires and Composite Clinical Disease Index for Assessing Rheumatoid Arthritis Activity: Identification of Cut-Off Points for Routine Care

Table 2

PASS thresholds for each measure defined by the 75th percentile of the cumulative distribution, for patient who rated their condition as PASS positive, by plotting ROC curves and identifying cut-offs that yielded 80% specificity and by plotting ROC curves and identifying cut-offs that yielded the smallest number of false-positives and false-negatives.

Variable	PASS + 75th percentile threshold	80% specificity cut-off	ROC cut-off	Sensitivity/specificity	AUC-ROC curve
ROAD (0–76)	1.00	1.10	1.50	92.7/60.1	0.788
PRO-CLARA (0–10)	2.50	2.60	2.90	89.1/82.7	0.933
RAID (0–10)	2.00	2.10	2.60	96.4/73.4	0.862
CDAI (0–76)	13.83	15.85	14.21	81.8/91.6	0.925