Immunoregulation of Bone Marrow-Derived Mesenchymal Stem Cells on the Chronic Cigarette Smoking-Induced Lung Inflammation in Rats

Figure 1

BMSCs mitigate the chronic cigarette smoking-induced lung injury, STAT5 phosphorylation, but they elevate iNOS expression in rats. The lung sections were stained with hematoxylin and eosin, and the mean linear intercept (MLI) and the mean alveolar numbers (MAN) per unit area in rats were determined (a). The levels of serum and lung iNOS (b) and STAT5 phosphorylation (c) were examined. Data are representative images (magnification ×400) and expressed as the means ± SD of individual group ( per group) from three separate experiments. , versus the control; versus the BMSCs.

(a)

(b)

(c)