Utility of C-Reactive Protein Levels for Early Prediction of Dengue Severity in Adults

Table 4

CRP level distributions by the 1997 World Health Organization dengue classification and phase of illness.

Phase of illness	Median CRP (range)/no, mg/L
	DF	Nonshock DHF	DSS
Febrile phase (days 1–3)	13.8 (0.7–56.2)/61	15.8 (0.6–139.3)/32	124.5 (30.7–205.5)/4	0.070	<0.001	0.008	0.001
Critical phase (days 4–6)	6 (0.8–215.5)/53	9.9 (0.5–71.1)/31	144 (—)/1	0.016	—	—	—
Convalescent phase (days 7–10)	3.3 (1.6–10.7)/8	—	1.2 (—)/1	—	—	—	—

CRP = C-reactive protein; DF = dengue fever; DHF = dengue hemorrhagic fever; DSS = dengue shock syndrome; no = number of patients.
¹DF versus nonshock DHF.
²DF versus DSS.
³Nonshock DHF versus DSS.
⁴DF/nonshock DHF versus DSS.