Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study

Table 1

Baseline characteristics in 157 patients with metastases^a.

Characteristic	Preoperative zoledronic acid group (group A; )	Control group (group B; )
Sex			0.871
Men	48	46
Women	33	30
Age (y)			0.205
Mean ± SD	54.6 ± 10.1	52.5 ± 11.0
Range	33–75	31–87
Primary tumor			0.293
Lung	30	19
Liver	11	19
Thyroid	14	8
Breast	7	10
Renal	6	7
Prostate	6	8
Other	7	5
Preoperative Frankel score			0.296
A	3	1
B	6	4
C	26	20
D	36	46
E	10	5
Number of spinal metastases			0.508
Single	74	67
Multiple	7	9
Complete arterial embolism			0.588
Yes	61	60
No	20	16
Tumor location			0.605
Cervical	14	17
Thoracic	35	34
Lumbar	32	25

SD: standard deviation.
^aThe Student’s -test was used for continuous variables, and chi-square analysis was used for categorical variables.