Clinical Study

Analysis of Erythrocyte C4d to Complement Receptor 1 Ratio: Use in Distinguishing between Infection and Flare-Up in Febrile Patients with Systemic Lupus Erythematosus

Table 4

Receiver operating characteristic (ROC) curve analysis of the utility of the C4d/CR1 ratio and serum CRP level in febrile SLE patients with infection.

RulesNumber(s)Sensitivity (%)Specificity (%)

AC4d/CR1 > 1.2447CRP > 4.6714.55100.0
CRP < 4.67313.6412.5
C4d/CR1 < 1.2447CRP > 4.67940.91100.0
CRP < 4.67940.9169.2

Total 22

BC4d/CR1 > 1.2447CRP > 2.2418.1880.0
CRP < 2.2000
C4d/CR1 < 1.2447CRP > 2.21350.0986.7
CRP < 2.2522.7371.4

Total 22