Impact of CYP1A1 Polymorphisms on Susceptibility to Chronic Obstructive Pulmonary Disease: A Meta-Analysis

Table 2

Genotype frequency distribution of CYP1A1 polymorphisms.

Polymorphisms	First author	Case				Control				HWE in controls	MAF in controls
			TT	TC	CC		TT	TC	CC
MspI (rs4646903)	Cheng	184	76	78	30	212	85	107	20	2.76	0.35
	Gaspar	75	49	25	1	90	64	21	5	2.97	0.17
	Korytina	275	213	54	8	387	277	102	8	0.15	0.15
	Putra	48	21	27		172	57	115		NA	NA
	Vibhuti	210	80	107	23	136	75	53	8	0.12	0.25
	Yang	101	28	49	24	80	35	31	14	2.24	0.37
			AA	AG	GG		AA	AG	GG
Ile/Val (rs1048943)	Gaspar	75	59	16	0	90	73	14	3	4.06	0.11
	Korytina	317	292	25	0	418	382	34	2	1.64	0.05
	Putra	48	28	20		172	93	79		NA	NA
	Vibhuti	210	141	46	23	136	109	24	3	1.38	0.11
	Wang	115	45	61	9	94	53	37	4	0.62	0.24

Sample size of case group or control group.
Gaspar recruited controls apart from Hardy-Weinberg equilibrium and thus these data were excluded from susceptibility analysis.
: sample size in case or control group; NA: not available; HWE: Hardy-Weinberg equilibrium; MAF: minor allele frequency.