Review Article
Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma
Table 1
Recurrent chromosomal aberrations observed in MM and their prognostic relevance.
| Aberration | Incidence | Outcome |
| Trisomies of chromosomes 3, 5, 7, 11, 15, 19, and 21 | 60% | Favorable | t(4;14) | 15% | Poor | t(11;14) | 20% | Favorable | t(14;16) | 6-7% | Poor | del(17p) | 8–10% | Poor |
|
|