BioMed Research International

Review Article

Trichomonas vaginalis Cysteine Proteinases: Iron Response in Gene Expression and Proteolytic Activity

Table 2

Expression at the mRNA and protein levels of cathepsin L-like and papain-like cysteine proteinases of Trichomonas vaginalis.
Type of CPIDNamebpaaContigOrientationREESTTbExp. reportsProteomeRef.
Accession numberTotalTvLI
CB-likeTVAG_488380 
gb∣XP_001323959.1
gi∣123483120		NA765255DS1133143′-5′400NRNRNR[25]
CL-likeTVAG_485880 
gb∣XP_001321164.1
gi∣123475979		NA1356452DS1133673′-5′NP101NRNRNR[25]
CL-likeTVAG_484350 
gb∣XP_001304351.1
gi123413805		NAa873291DS1140365′-3′NP92NRNRNR[25]
CB-likeTVAG_482410 
gb∣XP_001322190.1
gi∣123478051		NA864288DS1133473′-5′NP00NRNRNR[25]
CL-likeTVAG_46797 
gb∣XP_001326005.11 
gi∣1234921851 
gb∣AAV985822 
gi∣565671862 
gb∣CAA544383 
gi∣4548903		TvCP4915305DS1132805′-3′NP21519NRL/HL[7, 25, 27, 28, 35, 58, 65, 66, 71]
CL-likeTVAG_465470 
gb∣XP_001328382.1
gi∣123502829		NAa915305DS1132465′-3′NP00NRNRNR[25]
CL-likeTVAG_461630 
gb∣XP_001297865.1
gi∣123375585		NA702234DS1151363′-5′NP00NRNRNR[25]
CB-likeTVAG_454200 
gb∣XP_001329727.1
gi∣123508810		NA759253DS1132295′-3′NP00NRNRNR[25]
CL-likeTVAG_437820 
gb∣XP_001310334.1
gi∣123439119		NAa915305DS1137165′-3′200NRNRNR[25]
CL-likeTVAG_427120 
gb∣XP_001306414.1
gi∣123423610		NA405135DS1139105′-3′NP00NRNRNR[25]
CL-likeTVAG_427130 
gb∣XP_001306415.1
gi∣123423613		NA399133DS1139105′-3′NP40NRNRNR[25]
CL-likeTVAG_410260 
gb∣XP_001323249.1
gi∣123480189		TvCP12945315DS1133275′-3′NP293NRLNR[25]
CL-likeTVAG_405280 
gb∣XP_001325205.1
gi∣123488591		NAa918306DS1132933′-5′NP00NRNRNR[25]
CL-likeTVAG_398510 
gb∣XP_001304940.1
gi∣123416650		NA411137DS1139963′-5′300NRNRNR[25]
CL-likeTVAG_355480 
gb∣XP_001310117.1
gi∣123438675		TvCP4-like915305DS1137265′-3′100NRNRNR[25, 27]
CL-likeTVAG_328620 
gb∣XP_001313029.1
gi∣123448602		NA303101DS1136143′-5′NP00NRNRNR[25]
CL-likeTVAG_325040 
gb∣XP_001330238.1 
gi∣123975201		NAa873291DS1135695′-3′NP51NRNRNR[25]
CL-likeTVAG_302570 
gb∣XP_001320393.1
gi∣123474420		NA1479493DS1133845′-3′NP30NRNRNR[25]
CL-likeTVAG_298080 
gb∣XP_001316414.11 
gi∣1234573731 
gb∣ABX56032.14 
gi∣1610162004		TvCPT/
TvCP39		915305DS1134823′-5′11688LLN[25, 27–29, 57, 65, 66]
CL-likeTVAG_293170 
gb∣XP_001298580.1 gi∣123381478		NA399133DS1148725′-3′300NRNRNR[25]
CL- or
K-like		TVAG_267850 
gb∣XP_001579738.1
gi∣154413416		NAa960320DS1132155′-3′NP00NRNRNR[25]
CL-likeTVAG_257790 
gb∣XP_001313154.1
gi∣123448858		NA609203DS1136093′-5′NP10NRNRNR[25]
CL-, S-, or H-likeTVAG_242850 
gb∣XP_001311850.1
gi∣123446194		NA1419473DS1136575′-3′NP51NRNRNR[25]
CL-likeTVAG_228710 
gb∣XP_001580594.1
gi∣154415137		NA879293DS1132065′-3′NP10NRNRNR[25]
CL-likeTVAG_228450 
gb∣XP_001580568.1
gi∣154415085		NAa915305DS1132065′-3′100NRNRNR[25]
CL-likeTVAG_218830 
gb∣XP_001300036.1
gi∣123391254		NA399133DS1145103′-5′NP60NRNRNR[25]
CB-likeTVAG_216350 
gb∣XP_001317882.1  
gi∣123469339		NA723241DS1134435′-3′NP00NRNRNR[25]
CL-likeTVAG_202090 
gb∣XP_001327438.11  
gi∣1234986021 
gb∣CAA54435.13 
gi∣4522923		CP1927309DS1132593′-5′NP6912LLN[25, 27–29, 35, 65, 66, 71]
CH-likeTVAG_181310 
XP_001306268.1 GI:123422894		NA1464488DS1139185′-3′NP01NRNRNR[25]
CL-likeTVAG_164120 
gb∣XP_001325526.1 giI123490067		NAa915305DS1132875′-3′141NRNRNR[25]
CB-likeTVAG_159150 
gb∣XP_001298125.1 gi∣123377855		NA405135DS1150343′-5′NP00NRNRNR[25]
CL- or K-likeTVAG_151460 
gb∣XP_001300085.1 gi∣123391522		TvCP25855285DS1145005′-3′NP70NRNRNR[25, 33]
CL-likeTVAG_146680 
gb∣XP_001579911.1 gi∣154413764		NA951317DS1132135′-3′120NRNRNR[25]
CL-likeTVAG_135480 
gb∣XP_001290980.1 gi∣123299807		NAa792264DS1221123′-5′NP11NRNRNR[25]
CL- or H-likeTVAG_126090 
gb∣XP_001321671.1 gi∣123477003		NA1305435DS1133575′-3′NP53NRNRNR[25]
P-likeTVAG_096740 
gb∣XP_001313692.1 gi∣123449986		CP65a915305DS1135905′-3′NP00NRNRNR[25]
P-likeTVAG_090100 
gb∣XP_001314419.11 gi∣1239760111 
gb∣CAA54437.13 
gi∣4522963		CP3a954318DS1135543′-5′NP1789LLL[25, 27, 28, 35, 65, 66]
P-likeTVAG_057000 
gb∣XP_001319129.11 gi∣1234718641 
gb∣CAA54436.13 gi∣4522943		TvCP2a942314DS1134123′-5′319856LLN[25, 27, 31, 35, 65, 66]
P-likeTVAG_053440 
gb∣XP_001318243.1 gi∣123470070		NAa882294DS1134345′-3′NP10NRNRNR[25]
P-likeTVAG_052570 
gb∣XP_001308929.1 gi∣123435098		NA300100DS1137793′-5′NP00NRNRNR[25]
P-likeTVAG_047960 
gb∣XP_001330457.1 gi∣123976147		NAa900300DS1135523′-5′NP20NRNRNR[25]
P-likeTVAG_043620 
gb∣XP_001315639.1 giI123455797		NAa915305DS1135055′-3′NP00NRNRNR[25]
P-likeTVAG_040870 
gb∣XP_001315160.1 gi∣123454821		NA1386462DS1135203′-5′NP82NRNRNR[25]
P-likeTVAG_034140 
gb∣XP_001318458.1 gi∣123470506		NAa951317DS1134283′-5′NP200NRNRNR[25]
P-likeTVAG_028720 
gb∣XP_001326142.1 gi∣123492781		NA723241DS1132783′-5′900NRNRNR[25]
P-likeTVAG_003650 
gb∣XP_001324382.1 gi∣123484966		NAa930310DS1133063′-5′NP10NRNRNR[25]
P-likeTVAG_518810 
gb∣XP_001283092.1 gi∣123194565		NAa942314DS1367735′-3′NP71NRNRNR[25]
CB-like: cathepsin B-like CP; CL-like: cathepsin L-like CP; P-like: papain-like CP. ID: gene identification in the TrichDB (http://www.trichdb.org/) genome database or in PubMed database; NA: nonassigned name; bp: gene size in base pairs (bp); aa: protein size in amino acids (aa); contig: contig number identification; orientation: gene orientation in the contig; RE: number of repetitive elements close to CP localized in the same contig; NP: not present; EST and TvLI: Total of EST sequence and ESTs reported in low-iron conditions in TrichDB database, respectively; NR: nonreported data; H: high-iron conditions; N: normal iron conditions: L: low-iron conditions: T: upregulated genes in H or L iron concentrations.
aProteins presenting certain homology degree with TvCP4; btranscriptome information by Horváthová et al., 2012 [71]. 1Accession number reported by Carlton et al., 2007 [25]; 2accession number reported by Solano-González et al., 2007 [36]; 3accession number reported by Mallinson et al., 1994 [35]; 4accession number reported by Sommer et al., 2005 [65].