The Impact of Sequence of Chemotherapy and EGFR-TKI Treatment on Different EGFR Mutation Lung Adenocarcinoma

Table 4

Final multivariate model for progression-free survival and overall survival.

	Progression-free survival		Overall survival
	OR (95% CI)	value	OR (95% CI)	value
Poor PS: >2	1.5 (0.5–4.2)	0.58	1.9 (0.81–3.82)	0.49
Smoking	1.3 (0.6–4.7)	0.49	1.4 (0.7–2.2)	0.31
2nd-line C/T	1.7 (1.51–3.89)	0.03	1.8 (1.4–3.91)	0.01
EGFR mutation (L858R to 19Del)	2.2 (1.7–4.5)	0.02	2.6 (1.2–5.6)	0.01

OR: odds ratio; CI: confidence interval; PS: performance status; C/T: chemotherapy; EGFR: epidermal growth factor receptor gene.
values were obtained by multinominal logistic regression analysis.