Meningeal Melanomatosis: A Challenge for Timely Diagnosis

Figure 3

Light microscopy pictures of the cytological specimen of cerebrospinal fluid obtained from patient 1: (a) hematoxylin and eosin staining of the hypercellular sample, with large, hyperchromatic cells associated with erythrocytes; (b) atypical cells stained with Melan-A, a melanoma-specific marker; (c) Schmorl staining confirmed the presence of melanin (blue granular stain) in the cytoplasm; magnification, 20x.

(a)

(b)

(c)