In Vivo Confocal Microscopy of the Human Cornea in the Assessment of Peripheral Neuropathy and Systemic Diseases

Table 1

Corneal subbasal nerve densities on in vivo confocal microscopy in a range of systemic diseases.

	Corneal subbasal nerve density in patients (mm/mm^2)	Corneal subbasal nerve density in controls (mm/mm^2)
Diabetes type 1 [14]	20.6 ± 1.5	27.7 ± 1.1
Diabetes type 2 [24]	4.3 ± 1.5	13.5 ± 0.3
Parkinson’s disease [32]	15.0 ± 8.0	13.5 ± 5.0
Progressive supranuclear palsy [32]	15.0 ± 6.0	13.5 ± 5.0
Amyotrophic lateral sclerosis [36]	1.8 ± 0.4	2.3 ± 0.4
Idiopathic small fibre neuropathy [38]	4.4 ± 0.6	9.3 ± 0.6
Charcot-Marie-Tooth type 1A [41]	15.8 ± 1.5	26.7 ± 1.3
Chronic inflammatory demyelinating polyneuropathy [62]	18.1 ± 3.4	23.5 ± 3.6
Chemotherapy induced peripheral neuropathy [9]	6.8 ± 2.4	10.8 ± 3.8