Clinical Study

Effective Dose of Ramosetron for Prophylaxis of Postoperative Nausea and Vomiting in High-Risk Patients

Table 3

Rhodes index of nausea, vomiting, and retching (RINVR) and incidence of complete responses.

Group A
(N = 16)
Group B
(N = 16)
Group C
(N = 15)

During 0~1 hr
 Complete responses12 (75%)9 (56%)13 (87%)
 Occurrence score0.71 ± 1.160.82 ± 1.010.41 ± 0.94
 Distress score0.82 ± 1.810.71 ± 0.990.35 ± 0.86
 Experience score1.53 ± 2.811.53 ± 1.940.81 ± 1.80

During 1~6 hrs
 Complete responses13 (81%)10 (63%)12 (80%)
 Occurrence score0.76 ± 1.921.00 ± 1.580.53 ± 1.23
 Distress score0.65 ± 1.970.65 ± 1.110.29 ± 0.69
 Experience score1.50 ± 3.921.80 ± 2.720.88 ± 1.96

During 6~24 hrs
 Complete responses7 (44%)13 (81%)14 (93%)
 Occurrence score2.12 ± 2.741.18 ± 3.090.53 ± 1.74
 Distress score1.59 ± 2.500.94 ± 2.770.24 ± 0.75
 Experience score3.94 ± 5.252.25 ± 5.980.81 ± 2.56

During 24~48 hrs
 Complete responses14 (88%)13 (81%)14 (93%)
 Occurrence score0.47 ± 1.330.65 ± 1.540.47 ± 1.50
 Distress score0.35 ± 1.220.65 ± 1.660.29 ± 0.99
 Experience score0.88 ± 2.501.38 ± 3.260.81 ± 2.56

as compared with group A.
The values are shown as means ± SD or proportions of patients (%).