Clinical Study
Effective Dose of Ramosetron for Prophylaxis of Postoperative Nausea and Vomiting in High-Risk Patients
Table 3
Rhodes index of nausea, vomiting, and retching (RINVR) and incidence of complete responses.
| | Group A (N = 16) | Group B (N = 16) | Group C (N = 15) |
| During 0~1 hr | | | | Complete responses | 12 (75%) | 9 (56%) | 13 (87%) | Occurrence score | 0.71 ± 1.16 | 0.82 ± 1.01 | 0.41 ± 0.94 | Distress score | 0.82 ± 1.81 | 0.71 ± 0.99 | 0.35 ± 0.86 | Experience score | 1.53 ± 2.81 | 1.53 ± 1.94 | 0.81 ± 1.80 |
| During 1~6 hrs | | | | Complete responses | 13 (81%) | 10 (63%) | 12 (80%) | Occurrence score | 0.76 ± 1.92 | 1.00 ± 1.58 | 0.53 ± 1.23 | Distress score | 0.65 ± 1.97 | 0.65 ± 1.11 | 0.29 ± 0.69 | Experience score | 1.50 ± 3.92 | 1.80 ± 2.72 | 0.88 ± 1.96 |
| During 6~24 hrs | | | | Complete responses | 7 (44%) | 13 (81%) | 14 (93%) | Occurrence score | 2.12 ± 2.74 | 1.18 ± 3.09 | 0.53 ± 1.74 | Distress score | 1.59 ± 2.50 | 0.94 ± 2.77 | 0.24 ± 0.75 | Experience score | 3.94 ± 5.25 | 2.25 ± 5.98 | 0.81 ± 2.56 |
| During 24~48 hrs | | | | Complete responses | 14 (88%) | 13 (81%) | 14 (93%) | Occurrence score | 0.47 ± 1.33 | 0.65 ± 1.54 | 0.47 ± 1.50 | Distress score | 0.35 ± 1.22 | 0.65 ± 1.66 | 0.29 ± 0.99 | Experience score | 0.88 ± 2.50 | 1.38 ± 3.26 | 0.81 ± 2.56 |
|
|
as compared with group A. The values are shown as means ± SD or proportions of patients (%).
|