Evolution of Action Potential Alternans in Rabbit Heart during Acute Regional Ischemia

Figure 6

Comparison of simultaneous optical and electrical measurements inside the ischemic region after 4 (a), 7 (b), and 10 minutes (c) of artery occlusion. CL = 200 ms. Left, OAPA alternans maps. Interval between the isolines is 5%. Middle, optical (normalized to control, black trace) and electrical AP’s in mV at 0.5 mm (blue trace) and at 3 mm (red trace) recorded simultaneously in the location indicated by the white circle in the OAPA maps. Asterisks show stimulation artifacts. Right, overlapped optical, and electrical AP’s of odd (solid trace) and even (round-dotted trace) beats. Other notations are the same as in Figure 2.

(a)

(b)

(c)