Mutations Found in embCAB, embR, and ubiA Genes of Ethambutol-Sensitive and -Resistant Mycobacterium tuberculosis Clinical Isolates from China

Table 3

Mutants in embB, embA, embC, embR, and ubiA within the EMB-sensitive isolates.

Types	Locus, nucleotide change, and amino acid change					Number ()
	embB	embA	embC	embR	ubiA
1	WT	WT	WT	WT	WT	124
2	M306V (ATG-GTG)	WT	WT	WT	WT	11
3	M306L (ATG-CTG)	WT	WT	WT	WT	4
4	M306I (ATG-ATA)	WT	WT	WT	WT	1
5	M306I (ATG-ATT)	WT	WT	WT	WT	1
6	G406P (GGC-CCG)	WT	WT	WT	WT	1
7	G246R (GGC-CGC)	WT	WT	WT	WT	1
8	A307G (GCC-GGC)	WT	WT	WT	WT	1
9	N318S (AAC-AGC)	WT	WT	WT	WT	1
10	A439A (GCA-GCG)	WT	WT	WT	WT	1
11	L336P (CTG-CCG)	WT	WT	WT	WT	1
12	WT	V343L (GTG-TTG)	WT	WT	WT	1
13	WT	R380P (CGT-CCT)	WT	WT	WT	1
14	WT	WT	E305E (GAG-GAA)	WT	WT	1
15	WT	WT	WT	L125S (TTG-TCG)	WT	1
16	M306V (ATG-GTG)	WT	WT	R230W (CGT-TGG)	WT	1
17	WT	WT	WT	WT	I206I (ATC-ATT)	1