The MicroRNA3686 Inhibits the Proliferation of Pancreas Carcinoma Cell Line by Targeting the Polo-Like Kinase 1

Figure 5

Transfection of microRNA3686 in PANC1 cell reduced its capability of invasion and clone forming. (a) Cell invasion assay picture for scramble control or mir3686 mimic transfected PANC cell. (b) Quantification of cell invasion result between scramble control and mir3686 mimic transfected PANC1 cell indicated the significant different in cell invasion ability. Error bars represent standard errors of six repeated experiments. Significant differences between groups are shown by “,” which indicates ; (c) clonogenic cell survival assay indicated mir3686 significantly reduced the colonies formation in mir3686 mimic transfected cell.

(a)

(b)

(c)