Efficacy of Olanzapine Combined Therapy for Patients Receiving Highly Emetogenic Chemotherapy Resistant to Standard Antiemetic Therapy

Table 3

Changes of nausea grade and nausea control rate after receiving olanzapine combined with standard antiemetic therapy.

	Acute phase (0–24 h)		Delayed phase (24–120 h)		Overall phase (0–120 h)
	Without OLN	With OLN	Without OLN	With OLN	Without OLN	With OLN
Nausea grade
0	17 (34%)	43 (86%)	0 (0%)	21 (42%)	0 (0%)	20 (40%)
1	12 (24%)	6 (12%)	1 (2%)	26 (52%)	0 (0%)	26 (52%)
2	14 (28%)	1 (2%)	20 (40%)	3 (6%)	18 (36%)	4 (8%)
3	7 (14%)	0 (0%)	29 (58%)	0 (0%)	32 (64%)	0 (0%)
Nausea control rate^*	58%	98%	2%	94%	0%	92%
value^**

OLN: olanzapine, ^*nausea grade 0 or 1 (CTCAE ver. 4.0), and ^**McNemar test.