Characteristic Gene Expression Profiles of Human Fibroblasts and Breast Cancer Cells in a Newly Developed Bilateral Coculture System

Table 1

Enrichment analysis: upregulation in each cancer cell line.

#	Upregulation: GO processes in MCF7	value	FDR
1	Cellular process
2	Protein localization to cell junction
3	Regulation of cardiac muscle cell apoptotic process
#	Upregulation: GO processes in SKBR3	value	FDR
1	Cell cycle
2	Apoptotic process
3	Cellular metabolic process
#	Upregulation: GO processes in HCC1937	value	FDR
1	Nuclear division
2	Organelle fission
3	Cell division
#	Upregulation: metabolic networks in MCF7	value	FDR
1	Carbohydrate metabolism_TCA and tricarboxylic acids transport
2	Carbohydrate metabolism_propionate metabolism and transport
3	Vitamin, mediator, and cofactor metabolism_folic acid
#	Upregulation: metabolic networks in SKBR3	value	FDR
1	1-Hexadecanoyl-glycerol_3-phosphate pathway
2	1-Linoleoyl-glycerol_3-phosphate pathway
3	1-Oleoyl-glycerol_3-phosphate pathway
#	Upregulation: metabolic networks in HCC1937	value	FDR
1	Carbohydrate metabolism_pyruvate metabolism and transport
2	Lipid metabolism_triacylglycerol metabolism
3	N-Acetyl-D-galactosamine pathway