Characteristic Gene Expression Profiles of Human Fibroblasts and Breast Cancer Cells in a Newly Developed Bilateral Coculture System

Table 2

Enrichment analysis: downregulation in each cancer cell line.

#	Downregulation: GO processes in MCF7	value	FDR
1	Establishment of localization
2	Transport
3	Peptidylglycine modification
#	Downregulation: GO processes in SKBR3	value	FDR
1	Regulation of apoptotic process
2	Regulation of programmed cell death
3	Response to mechanical stimulus
#	Downregulation: GO processes in HCC1937	value	FDR
1	Acute inflammatory response
2	Response to metal ion
3	Response to inorganic substance
#	Downregulation: metabolic networks in MCF7	value	FDR
1	Lysophosphatidylserine pathway
2	Carbohydrate metabolism_glycolysis, glycogenesis, and glucose transport
3	1,2-Didocosapentaenoyl-sn-glycerol_3-phosphate pathway
#	Downregulation: metabolic networks in SKBR3	value	FDR
1	GalNAcbeta1-3Gal pathway
2	Pentose phosphate pathways and transport
3	(L)-Alanine pathways and transport
#	Downregulation: metabolic networks in HCC1937	value	FDR
1	Phosphatidylethanolamine pathway
2	O-Hexanoyl-(L)-carnitine pathway
3	Myristoyl-L-carnitine pathway