Research Article
Characteristic Gene Expression Profiles of Human Fibroblasts and Breast Cancer Cells in a Newly Developed Bilateral Coculture System
Table 3
Enrichment analysis: upregulation in fibroblasts.
| # | Upregulation: GO processes with MCF7 | value | FDR |
| 1 | Regulation of programmed cell death | | | 2 | Regulation of cell death | | | 3 | Regulation of apoptotic process | | |
| # | Upregulation: GO processes with SKBR3 | value | FDR |
| 1 | Cellular component organization | | | 2 | Cellular component organization or biogenesis | | | 3 | Response to stress | | |
| # | Upregulation: GO processes with HCC1937 | value | FDR |
| 1 | Single-organism cellular process | | | 2 | Single-organism process | | | 3 | Response to hypoxia | | |
| # | Upregulation: metabolic networks with MCF7 | value | FDR |
| 1 | (S)-Citrulline pathway | | | 2 | Glycine pathways and transport | | | 3 | L-Serine pathways and transport | | |
| # | Upregulation: metabolic networks with SKBR3 | value | FDR |
| 1 | Carbohydrate metabolism_glycolysis, glycogenesis, and glucose transport | | | 2 | Carbohydrate metabolism_fructose metabolism and transport | | | 3 | (L)-Alanine pathways and transport | | |
| # | Upregulation: metabolic networks with HCC1937 | value | FDR |
| 1 | Carbohydrate metabolism_glycolysis, glycogenesis, and glucose transport | | | 2 | Carbohydrate metabolism_fructose metabolism and transport | | | 3 | Carbohydrate metabolism_galactose metabolism and transport | | |
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