Research Article

Characteristic Gene Expression Profiles of Human Fibroblasts and Breast Cancer Cells in a Newly Developed Bilateral Coculture System

Table 3

Enrichment analysis: upregulation in fibroblasts.

#Upregulation: GO processes with MCF7 valueFDR

1Regulation of programmed cell death
2Regulation of cell death
3Regulation of apoptotic process

#Upregulation: GO processes with SKBR3 valueFDR

1Cellular component organization
2Cellular component organization or biogenesis
3Response to stress

#Upregulation: GO processes with HCC1937 valueFDR

1Single-organism cellular process
2Single-organism process
3Response to hypoxia

#Upregulation: metabolic networks with MCF7 valueFDR

1(S)-Citrulline pathway
2Glycine pathways and transport
3L-Serine pathways and transport

#Upregulation: metabolic networks with SKBR3 valueFDR

1Carbohydrate metabolism_glycolysis, glycogenesis, and glucose transport
2Carbohydrate metabolism_fructose metabolism and transport
3(L)-Alanine pathways and transport

#Upregulation: metabolic networks with HCC1937 valueFDR

1Carbohydrate metabolism_glycolysis, glycogenesis, and glucose transport
2Carbohydrate metabolism_fructose metabolism and transport
3Carbohydrate metabolism_galactose metabolism and transport