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BioMed Research International
Volume 2015 (2015), Article ID 963574, 8 pages
http://dx.doi.org/10.1155/2015/963574
Clinical Study

Five-Year Follow-Up of Concomitant Accelerated Hypofractionated Radiation in Advanced Squamous Cell Carcinoma of the Buccal Mucosa: A Retrospective Cohort Study

1Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
2Department of Radiation Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
3Aga khan University, Karachi, Pakistan
4Lahore Medical and Dental College, Lahore, Pakistan

Received 27 December 2014; Revised 18 April 2015; Accepted 25 April 2015

Academic Editor: Quintin Pan

Copyright © 2015 Hassan Iqbal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. K. Chhetri, J. D. Rawnsley, and T. C. Calcaterra, “Carcinoma of the buccal mucosa,” Otolaryngology—Head and Neck Surgery, vol. 123, no. 5, pp. 566–571, 2000. View at Publisher · View at Google Scholar · View at Scopus
  2. S. Dixit, R. K. Vyas, R. B. Toparani, H. A. Baboo, and D. D. Patel, “Surgery versus surgery and postoperative radiotherapy in squamous cell carcinoma of the buccal mucosa: a comparative study,” Annals of Surgical Oncology, vol. 5, no. 6, pp. 502–510, 1998. View at Publisher · View at Google Scholar · View at Scopus
  3. J. P. Pignon, J. Bourhis, C. Domenge, and L. Designé, “Chemotherapy added to locoregional treatment for head neck squamous cell cancer: three meta analyses of updated individual data. MACH-NC Collaborative Group. Meta Analyses of Chemotherapy on Head and Neck Cancer,” The Lancet, vol. 355, no. 9208, pp. 949–955, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. J.-P. Pignon, A. le Maître, E. Maillard, and J. Bourhis, “Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients, MACH-NC Collaborative Group,” Radiotherapy and Oncology, vol. 92, no. 1, pp. 4–14, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Bourhis, N. Syz, and J. Overgaard, “Conventional versus modified fractionated radiotherapy: meta-analysis based on individual data of patients with head and squamous-cell carcinoma (HNSCC),” Radiotherapy & Oncology, vol. 64, supplement 1, p. S25, 2003. View at Google Scholar
  6. K. Madhava, A. Hartley, M. Wake, J. C. Watkinson, and J. Glaholm, “Carbop latin and chemoradiotherapy schedule for squamous cell carcinoma of the head and neck,” Clinical Oncology, vol. 18, pp. 77–81, 2006. View at Google Scholar
  7. J. Tobias, K. Monson, N. Gupta et al., “Does chemotherapy have a role in management of patients with advanced head and neck cancer: early results from the UK head and neck cancer (UKHAN) trial,” in Proceedings of the American Society of Clinical Oncology Annual Meeting (ASCO '01), vol. 20 of Abstract 888, San Francisco, Calif, USA, May 2001.
  8. M. K. Nair, R. Sankaranarayanan, and T. K. Padmanabhan, “Evaluation of the role of radiotherapy in the management of carcinoma of the buccal mucosa,” Cancer, vol. 61, no. 7, pp. 1326–1331, 1988. View at Publisher · View at Google Scholar · View at Scopus
  9. N. D. Bloom and R. H. Spiro, “Carcinoma of the cheek mucosa. A retrospective analysis,” The American Journal of Surgery, vol. 140, no. 4, pp. 556–559, 1980. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Bourhis, C. Amand, and J. Pignon, “Update of MACH-NC (meta-analysis of chemotherapy in head & neck cancer) database focused on concomitant chemoradiotherapy,” Journal of Clinical Oncology, vol. 22, supplement 14S, p. 5505, 2004. View at Google Scholar
  11. The Department of Veterans Affairs Laryngeal Cancer Study Group, “Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer,” The New England Journal of Medicine, vol. 324, no. 24, pp. 1685–1690, 1991. View at Publisher · View at Google Scholar · View at Scopus
  12. D. E. Schuller, B. Metch, D. W. Stein, D. Mattox, and J. D. McCracken, “Preoperative chemotherapy in advanced resectable head and neck cancer: final report of the Southwest Oncology Group,” The Laryngoscope, vol. 98, no. 11, pp. 1205–1211, 1988. View at Google Scholar · View at Scopus
  13. A. A. Forastiere, M. Maor, R. S. Weber et al., “Longterm results of Intergroup RTOG 91-11: a phase III trial to preserve the larynxInduction cisplatin/5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy,” Journal of Clinical Oncology, vol. 24, 284s, abstract 5517, 2006, ASCO Annual Meeting Proceedings. View at Google Scholar
  14. A. G. Bernal, J. J. Cruz, P. Sánchez et al., “Four-day continuous infusion of cisplatin and 5-fluorouracil in head and neck cancer,” Cancer, vol. 63, no. 10, pp. 1927–1930, 1989. View at Publisher · View at Google Scholar · View at Scopus
  15. M. R. Posner, D. M. Hershock, C. R. Blajman et al., “Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. TAX 324 Study Group,” The New England Journal of Medicine, vol. 357, no. 17, pp. 1705–1715, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. J. B. Vermorken, E. Remenar, C. van Herpen et al., “Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer,” The New England Journal of Medicine, vol. 357, no. 17, pp. 1695–1704, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. W. E. Samlowski, H. Gundacker, J. P. Kuebler et al., “Evaluation of gemcitabine in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a Southwest Oncology Group Phase II study,” Investigational New Drugs, vol. 19, no. 4, pp. 311–315, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Hitt, D. Castellano, M. Hidalgo et al., “Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck,” Annals of Oncology, vol. 9, no. 12, pp. 1347–1349, 1998. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Jamshed, R. Hussain, and H. Iqbal, “Gemcitabine and cisplatin followed by chemo-radiation for advanced nasopharyngeal carcinoma,” Asian Pacific Journal of Cancer Prevention, vol. 15, no. 2, pp. 899–904, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. K. Tomihara, H. Fuse, W. Heshiki et al., “Gemcitabine chemotherapy induces phenotypic alterations of tumor cells that facilitate antitumor T cell responses in a mouse model of oral cancer,” Oral Oncology, vol. 50, no. 5, pp. 457–467, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. H. R. Whithers, J. M. G. Taylor, and B. Maciejewski, “The hazard of accelerated tumor clonogen repopulation during radiotherapy,” Acta Oncologica, vol. 27, no. 2, pp. 131–146, 1988. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Sanghera, C. McConkey, K.-F. Ho, J. Glaholm, and A. Hartley, “Hypofractionated accelerated radiotherapy with concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck,” International Journal of Radiation Oncology, Biology and Physics, vol. 67, no. 5, pp. 1342–1351, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. W. Budach, T. Hehr, V. Budach, C. Belka, and K. Dietz, “A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck,” BMC Cancer, vol. 6, article 28, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. J. F. Fowler, “Is there an optimum overall time for head and neck radiotherapy? A review, with new modelling,” Clinical Oncology, vol. 19, no. 1, pp. 8–22, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. J. F. Fowler, “Optimum overall times II: extended modelling for head and neck radiotherapy,” Clinical Oncology, vol. 20, no. 2, pp. 113–126, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. A. K. Chan, P. Sanghera, B. A. Choo et al., “Hypofractionated accelerated radiotherapy with concurrent carboplatin for locally advanced squamous cell carcinoma of the head and neck,” Clinical Oncology, vol. 23, no. 1, pp. 34–39, 2011. View at Publisher · View at Google Scholar · View at Scopus