Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

Figure 9

Monkeypox virus colocalizes with apoptotic cells. Representative liver section from Congo Basin MPXV infected prairie dog on day 12 p.i. Apoptotic cells (red-brown nuclei) tended to also stain for poxvirus (blue-black cytoplasmic staining, arrows). (Immunoperoxidase method with Vector Red chromogen, alkaline phosphatase method with BCIP/NBT Chromogen; 400x original magnification, scale bar = 20 μm; methyl green counterstain.)